Health

Friday, November 17, 2006

Zyrtec

What is the most important information I should know about Zyrtec?
• Use caution when driving, operating machinery, or performing other hazardous activities. Zyrtec may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
• Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Zyrtec.




What is Zyrtec?
• Zyrtec is an antihistamine. Antihistamines prevent sneezing, runny nose, itching and watering of the eyes, and other allergic symptoms.
• Zyrtec is used to treat allergies, hives (urticaria), and other allergic inflammatory conditions.
• Zyrtec may also be used for purposes other than those listed in this medication guide.




Who should not take Zyrtec?
• Before taking this medication, tell your doctor if you have kidney or liver disease. You may need a lower dose or special monitoring during your therapy with Zyrtec.
• Zyrtec is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take Zyrtec without first talking to your doctor if you are pregnant.
• Zyrtec passes into breast milk and may affect a nursing baby. Do not take Zyrtec without first talking to your doctor if you are breast-feeding a baby.
• If you are over 60 years of age, you may be more likely to experience side effects from Zyrtec. You may require a lower dose of this medication.




How should I take Zyrtec?
• Take Zyrtec exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Zyrtec can be taken with or without food.
• Zyrtec is usually taken once daily. Follow your doctor's instructions.
• Store Zyrtec at room temperature away from moisture and heat.




What happens if I miss a dose?
• Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take a double dose of this medication.




What happens if I overdose?
• Seek emergency medical attention.
• Symptoms of a Zyrtec overdose are not well known, but extreme sleepiness, confusion, and weakness may be expected.




What should I avoid while taking Zyrtec?
• Use caution when driving, operating machinery, or performing other hazardous activities. Zyrtec may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities.
• Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking Zyrtec.




What are the possible side effects of Zyrtec?
• Stop taking Zyrtec and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
• Other, less serious side effects may be more likely to occur. Continue to take Zyrtec and talk to your doctor if you experience
· sleepiness, fatigue, or dizziness;
· headache; or
· dry mouth.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Zyrtec?
• Before taking this medication, tell your doctor if you are taking any of the following medicines:
· medications for anxiety or sleep such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);
· medications for depression such as amitriptyline (Elavil), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil);
· other cough, cold, or allergy medicines; or
· any other medications that cause drowsiness, sleepiness, or relaxation.
• Heavy sedation may occur if Zyrtec is taken with any of the medicines listed above.
• Drugs other than those listed here may also interact with Zyrtec. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Zyprexa

What is the most important information I should know about Zyprexa?
• Zyprexa is not for use in psychotic conditions that are related to dementia. Zyprexa has caused fatal heart attack and stroke in older adults with dementia-related conditions.
• Zyprexa may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Zyprexa.
• Do not stop taking Zyprexa without first talking to your doctor. It may be at least 4 weeks before you begin to feel better, and you may need to take the medication for longer than 4 weeks. Follow your doctor's instructions. It is important to take Zyprexa regularly to get the most benefit.
• Do not take Zyprexa for longer than 8 weeks unless your doctor has told you to.
• Zyprexa can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
• Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
• Avoid drinking alcohol, which can increase some of the side effects of Zyprexa.
• Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by Zyprexa.
• Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking Zyprexa.




What is Zyprexa?
• Zyprexa is an antipsychotic medication. It works by changing the actions of chemicals in the brain.
• Zyprexa is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression).
• Zyprexa may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Zyprexa?
• Zyprexa is not for use in psychotic conditions that are related to dementia. Zyprexa has caused fatal heart attack and stroke in older adults with dementia-related conditions.
• Before taking Zyprexa, tell your doctor if you have:
· liver disease;
· kidney disease;
· heart disease, high blood pressure, heart rhythm problems;
· a history of heart attack or stroke;
· a history of breast cancer;
· seizures or epilepsy;
· a personal or family history of diabetes;
· an enlarged prostate or difficulty urinating;
· glaucoma; or
· trouble swallowing.
• If you have any of these conditions, you may not be able to use Zyprexa, or you may need a dosage adjustment or special tests during treatment.
• Zyprexa may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking Zyprexa.
• The olanzapine orally disintegrating tablet (Zyprexa Zydis) may contain phenylalanine. Talk to your doctor before using this form of Zyprexa if you have phenylketonuria (PKU).
• FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
• Zyprexa can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.




How should I take Zyprexa?
• Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.
• Do not take Zyprexa for longer than 8 weeks unless your doctor has told you to.
• Take each tablet with a full glass of water.
• Zyprexa can be taken with or without food.
• Zyprexa is usually taken once a day. Follow your doctor's instructions.
• To take Zyprexa orally disintegrating tablets (Zyprexa Zydis):
· Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.
· Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.
· Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.
· Swallow several times as the tablet dissolves. If desired, you may drink liquid to help swallow the dissolved tablet.
• It is important to take Zyprexa regularly to get the most benefit.
• Do not stop taking Zyprexa without first talking to your doctor. It may be at least 4 weeks before you begin to feel better, and you may need to take the medication for longer than 4 weeks. Follow your doctor's instructions. It is important to take Zyprexa regularly to get the most benefit.
• To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. It is important that you not miss any scheduled visits to your doctor.
• Store Zyprexa at room temperature away from moisture and heat.




What happens if I miss a dose?
• Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.




What happens if I overdose?
• Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of an Zyprexa overdose may include drowsiness, agitation, aggression, slurred speech, confusion, increased heart rate, jerky or uncontrolled muscle movements, trouble breathing, or fainting.




What should I avoid while taking Zyprexa?
• Zyprexa can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
• Dizziness may be more likely to occur when you rise from a sitting or lying position. Rise slowly to prevent dizziness and a possible fall.
• Avoid drinking alcohol, which can increase some of the side effects of Zyprexa.
• Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by Zyprexa.
• Avoid becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking Zyprexa.




What are the possible side effects of Zyprexa?
• Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
• Stop using Zyprexa and call your doctor at once if you have any of these serious side effects:
· fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;
· jerky muscle movements you cannot control;
· sudden numbness or weakness, especially on one side of the body;
· sudden headache, confusion, problems with vision, speech, or balance;
· increased thirst, frequent urination, excessive hunger, or weakness;
· feeling light-headed, fainting; or
· unusual thoughts or behavior, hallucinations, or thoughts about hurting yourself.
• Continue taking Zyprexa and talk to your doctor if you have any of these less serious side effects:
· dizziness, drowsiness, or weakness;
· constipation;
· dry mouth;
· swelling in your hands or feet;
· back pain;
· weight gain, increased appetite; or
· upset stomach.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Zyprexa?
• Before taking Zyprexa, tell your doctor if you are taking any of the following medicines:
· a medication to treat high blood pressure or a heart condition;
· carbamazepine (Tegretol);
· fluvoxamine (Luvox); or
· a medication to treat Parkinson's disease including levodopa (Sinemet, Larodopa, Atamet), selegiline (Eldepryl, Emsam), pramipexole (Mirapex), ropinirole (Requip), and others.
• If you are using any of these drugs, you may not be able to use Zyprexa, or you may need dosage adjustments or special tests during treatment.
• There may be other drugs not listed that can affect Zyprexa. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Zomig

What is the most important information I should know about Zomig?
• Do not take this medication without first talking to your doctor if you have heart disease including angina (chest pain), history of a heart attack, or high blood pressure. Serious, even fatal, side effects involving the heart have been reported with Zomig and other similar medicines.
• Do not take Zomig if the headache you are experiencing is not like other migraines that you have had.
• Never take more of this medication than is prescribed by your doctor. If your symptoms are not being treated, contact your doctor.
• Zomig may cause dizziness or drowsiness. Use caution when driving, operating machinery, or performing other hazardous activities until you can evaluate the effects of the medication.




What is Zomig?
• Zomig is a headache medicine. It is believed to work by causing vasoconstriction (narrowing) of blood vessels (arteries and veins) around the brain. Zomig also reduces the release of substances in the body that contribute to headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.
• Zomig is used to treat vascular headaches such as migraines. Zomig will not prevent migraines. It will only treat a migraine that is already occurring.
• Zomig may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Zomig?
• Do not take Zomig without first talking to your doctor if you
· have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) in the last 14 days;
· have taken an ergot-based medication within the last 24 hours--ergot-based medicines include methysergide (Sansert), ergotamine (Ergostat, Medihaler Ergotamine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray), and ergotamine combination products (Cafergot, Ercaf, Wigraine, Cafatine, Cafatine-PB, Cafetrate);
· have taken almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or sumatriptan (Imitrex) within the last 24 hours;
· have basilar or hemiplegic migraine headaches;
· have had a heart attack, have angina (chest pain), have irregular heartbeats, or have another type of heart disease;
· have a history of stroke or transient ischemic attack (TIA or "mini-stroke");
· are experiencing a headache that is not like other migraines you have had; or
· have an allergy to Zomig or another similar medicine such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), or sumatriptan (Imitrex).
• Taking Zomig may be dangerous if you have any of the conditions, or have taken any of the medications, listed above.
• Before taking Zomig, tell your doctor if you have
· risk factors for heart disease such as high blood pressure, a family history of heart disease, high cholesterol (a type of fat in the blood), are overweight, have diabetes, smoke cigarettes, are postmenopausal, or are a male over 40 years of age;
· liver disease;
· kidney disease; or
· seizures or epilepsy.
• You may not be able to take Zomig, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Each 2.5 mg Zomig-ZMT orally disintegrating tablet contains 2.81 mg phenylalanine. Each 5 mg Zomig-ZMT tablet contains 5.62 mg phenylalanine. Individuals with phenylketonuria may need to monitor their intake of this additive.
• Zomig is in the FDA pregnancy category C. This means that it is not known whether Zomig will be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
• It is not known whether Zomig passes into human breast milk. Do not take Zomig without first talking to your doctor if you are breast-feeding a baby.




How should I take Zomig?
• Take Zomig exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take Zomig as soon as you notice symptoms of a migraine, or at any time during an attack.
• Take one or one-half regular Zomig tablet with a glass of water, as directed by your doctor.
• Administration with liquid is not necessary for the Zomig-ZMT orally disintegrating tablets. Just prior to taking a dose, peel open the blister pack and place the tablet on the tongue, where it will dissolve and be swallowed with the saliva. The Zomig-ZMT tablets should not be broken.
• Use the nasal spray as directed by your healthcare provider. Blow your nose gently before use. Remove the protective cap just before use. Hold the nasal sprayer device with your fingers and thumb. Do not press the plunger until you have put the tip of the device into your nostril. Block one nostril by pressing on the side of the nose with your finger. Either nostril can be used. Put the tip of the sprayer into the other nostril as far as feels comfortable and tilt your head slightly back. Breathe in gently through the nose and press the plunger firmly with your thumb at the same time. Keep your head slightly tilted back and remove the tip from your nose. Breathe gently through your mouth for 5-10 seconds. You may feel liquid in your nose or the back of your throat. This is normal and will soon pass.
• If your symptoms do not improve, contact your doctor before taking any more doses of Zomig.
• If your symptoms go away and then return, you can take a another dose of Zomig every 2 hours, if needed, up to a maximum of 10 mg in 24 hours unless otherwise directed by your doctor. Never take more than this amount. Any single form or combination of Zomig regular tablets, orally-disintegrating tablets, and nasal spray should not exceed 10 mg in 24 hours.
• Store Zomig at room temperature away from moisture, heat, and the reach of children. Throw away an unused medication on the expiration date.




What happens if I miss a dose of Zomig?
• Since Zomig is taken to treat migraines as they occur and not to prevent them, missing a dose does not usually occur. Take only the doses you need, according to your doctor's instructions.




What happens if I overdose with Zomig?
• Seek emergency medical attention if an overdose is suspected.
• Symptoms of a Zomig overdose are not well known but may include sedation.




What should I avoid while taking Zomig?
• Zomig may cause dizziness or drowsiness. Use caution when driving, operating machinery, or performing other hazardous activities until you can evaluate the effects of the medication.




What are the possible side effects of Zomig?
• If you experience any of the following serious side effects, stop taking Zomig and seek emergency medical attention or contact your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
· severe or prolonged chest pain or an irregular heartbeat;
· chest, neck, or jaw pain, tightness, or heaviness;
· sudden or severe stomach pain;
· problems seeing; or
· unusual weakness or numbness.
• Other, less serious side effects may be more likely to occur. Continue to take Zomig and talk to your doctor if you experience
· dry mouth;
· unusual taste in the mouth;
· nausea;
· muscle tiredness or weakness;
· tightness, heaviness, or pressure on a body part (other than the chest, neck, or jaw);
· drowsiness or dizziness; or
· tingling, tightness, warmth, or heaviness in a body part.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Zomig?
• Do not take Zomig if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), tranylcypromine (Parnate), or phenelzine (Nardil) within the last 14 days. The combination could cause seizures, nausea, vomiting, sweating, flushing, and dizziness.
• Do not take Zomig if you have taken any of the following medicines within the previous 24 hours:
· an ergot-based medication such as methysergide (Sansert), ergotamine (Ergostat, Medihaler Ergotamine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray), an ergotamine combination product (Cafergot, Ercaf, Wigraine, Cafatine, Cafatine-PB, Cafetrate), and others; or
· almotriptan (Axert), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or sumatriptan (Imitrex).
• Taking Zomig within 24 hours of any of the medicines listed above may be dangerous.
• Before taking Zomig, tell your doctor if you are taking a selective serotonin reuptake inhibitor (SSRI) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft). You may not be able to take Zomig, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed.
• Before taking Zomig, talk to your doctor if you are taking cimetidine (Tagamet, Tagamet HB). You may require a dosage adjustment or special monitoring during treatment.
• Drugs other than those listed here may also interact with Zomig. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Zoloft

What is the most important information I should know about Zoloft?
You may have an increased risk of suicidal thoughts or behavior at the start of treatment with an antidepressant medication, especially if you are under 18 years old. Talk with your doctor about this risk. While you are taking Zoloft you will need to be monitored for worsening symptoms of depression and/or suicidal thoughts during the first weeks of treatment, or whenever your dose is changed. In addition to you watching for changes in your own symptoms, your family or other caregivers should be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Contact your doctor promptly if you have any of the following side effects, especially if they are new symptoms or if they get worse: mood changes, anxiety, panic attacks, trouble sleeping, irritability, agitation, aggressiveness, severe restlessness, mania (mental and/or physical hyperactivity), thoughts of suicide or hurting yourself. Do not take Zoloft together with pimozide (Orap), or a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate). You must wait at least 14 days after stopping an MAOI before you can take Zoloft. After you stop taking Zoloft, you must wait at least 14 days before you start taking an MAOI. SSRI antidepressants may cause serious or life-threatening lung problems in newborn babies whose mothers take the medication during pregnancy. However, you may have a relapse of depression if you stop taking your antidepressant during pregnancy. If you are planning a pregnancy, or if you become pregnant while taking Zoloft, do not stop taking the medication without first talking to your doctor.

What is Zoloft?
Zoloft is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Zoloft affects chemicals in the brain that may become unbalanced and cause depression, panic, anxiety, or obsessive-compulsive symptoms.

Zoloft is used to treat depression, obsessive-compulsive disorder, panic disorder, anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).

Zoloft may also be used for purposes other than those listed in this medication guide.


What should I discuss with my healthcare provider before taking Zoloft?
You may have an increased risk of suicidal thoughts or behavior at the start of treatment with an antidepressant medication, especially if you are under 18 years old. Talk with your doctor about this risk. While you are taking Zoloft you will need to be monitored for worsening symptoms of depression and/or suicidal thoughts during the first weeks of treatment, or whenever your dose is changed. In addition to you watching for changes in your own symptoms, your family or other caregivers should be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks.

Do not use Zoloft if you are using pimozide (Orap), or an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), rasagiline (Azilect), or selegiline (Eldepryl, Emsam). Serious and sometimes fatal reactions can occur when these medicines are taken with Zoloft. You must wait at least 14 days after stopping an MAO inhibitor before you can take Zoloft. After you stop taking Zoloft, you must wait at least 14 days before you start taking an MAOI.
Before taking Zoloft, tell your doctor if you have:

liver or kidney disease;
seizures or epilepsy;

bipolar disorder (manic depression); or

a history of drug abuse or suicidal thoughts.

If you have any of these conditions, you may not be able to use Zoloft, or you may need a dosage adjustment or special tests.

FDA pregnancy category C. SSRI antidepressants may cause serious or life-threatening lung problems in newborn babies whose mothers take the medication during pregnancy. However, you may have a relapse of depression if you stop taking your antidepressant during pregnancy. If you are planning a pregnancy, or if you become pregnant while taking Zoloft, do not stop taking the medication without first talking to your doctor. It is not known whether Zoloft passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Zoloft?
Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from the medication.

Take each tablet with water.
Zoloft may be taken with or without food.

Try to take the medicine at the same time each day. Follow the directions on your prescription label.

The oral liquid form of this medicine must be diluted before you take it. To be sure you get the correct dose, measure the liquid with medicine dropper provided, not with a regular table spoon. Mix the dose with 4 ounces (one-half cup) of water, ginger ale, lemon/lime soda, lemonade, or orange juice. Do not use any other liquids to dilute the medicine. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

It may take 4 weeks or longer before you start feeling better. Do not stop using Zoloft without first talking to your doctor. You may have unpleasant side effects if you stop taking this medication suddenly. Store Zoloft at room temperature away from moisture and heat.

What happens if I miss a dose of Zoloft?
Take the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take extra medicine to make up the missed dose.


What happens if I overdose with Zoloft?
Seek emergency medical attention if you think you have taken too much of this medication. Symptoms of a Zoloft overdose may include dizziness, drowsiness, nausea, vomiting, rapid heartbeat, agitation, tremor, confusion, seizures, and coma.

What should I avoid while taking Zoloft?
Avoid drinking alcohol, which can increase some of the side effects of Zoloft.
Do not take the liquid form of Zoloft if you are taking disulfiram (Antabuse). Liquid Zoloft may contain alcohol and you could have a severe reaction to the disulfiram.

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, medicine for seizures, other medication for depression or anxiety). They can add to sleepiness caused by Zoloft.

Zoloft can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What are the possible side effects of Zoloft?
Get emergency medical help if you have any of these signs of an allergic reaction: skin rash or hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Contact your doctor promptly if you have any of the following side effects, especially if they are new symptoms or if they get worse: mood changes, anxiety, panic attacks, trouble sleeping, irritability, agitation, aggressiveness, severe restlessness, mania (mental and/or physical hyperactivity), thoughts of suicide or hurting yourself.
Call your doctor at once if you have any of these serious side effects:

seizure (convulsions);

tremors, shivering, muscle stiffness or twitching;

problems with balance or coordination; or

agitation, confusion, sweating, fast heartbeat.

Other less serious side effects are more likely to occur, such as:

feeling nervous, restless, or unable to sit still;

drowsiness, dizziness, weakness;

sleep problems (insomnia);

nausea, diarrhea, dry mouth, or changes in appetite or weight; or

decreased sex drive, impotence, or difficulty having an orgasm.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect Zoloft?
Talk to your doctor before taking any medicine for pain, arthritis, fever, or swelling. This includes aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn), diclofenac (Voltaren), indomethacin, piroxicam (Feldene), nabumetone (Relafen), etodolac (Lodine), and others. Taking any of these drugs with Zoloft may cause you to bruise or bleed easily.

Before taking Zoloft, tell your doctor if you are using any of the following medicines:

tramadol (Ultram, Ultram ER, Ultracet);

digitoxin (Crystodigin);

phenytoin (Dilantin), valproate (Depacon, Depakene);

lithium (Lithobid, Eskalith);

a blood thinner such as warfarin (Coumadin);

any other antidepressants such as amitriptyline (Elavil), citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), or paroxetine (Paxil);

almotriptan (Axert), frovatriptan (Frova), sumatriptan (Imitrex), naratriptan (Amerge), rizatriptan (Maxalt), or zolmitriptan (Zomig); or

heart rhythm medication such as flecainide (Tambocor), propafenone (Rhythmol), and others.

If you are using any of these drugs, you may not be able to use Zoloft, or you may need dosage adjustments or special tests during treatment.

There may be other drugs not listed that can affect Zoloft. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


Where can I get more information on Zoloft?
Your pharmacist has additional information about Zoloft written for health professionals that you may read.
What does my medication look like?
Sertraline is available with a prescription under the brand name Zoloft. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

Zoloft 25 mg-capsule-shaped, green, film-coated, scored tablets

Zoloft 50 mg--capsule-shaped, light-blue, film-coated, scored tablets

Zoloft 100 mg--capsule-shaped, light-yellow, film-coated, scored tablets

Zoloft Oral Concentrate 20 mg/mL-clear, colorless solution with a menthol scent

Zocor

What is the most important information I should know about Zocor?
• Rare cases of muscle problems and liver problems have been associated with the use of Zocor and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes, abdominal pain, unexplained fatigue, dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems.
• Do not take Zocor without first talking to your doctor if you have liver disease.
• Alcohol and Zocor can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined.
• Do not take Zocor if you are pregnant, could become pregnant during treatment, or if you are breast-feeding a baby.




What is Zocor?
• Zocor is an HMG CoA reductase inhibitor. Zocor blocks the production of cholesterol (a type of fat) in the body.
• Zocor is used to reduce the total amounts of cholesterol, LDL (bad) cholesterol, triglycerides (another type of fat), and apolipoprotein B (a protein needed to make cholesterol) in your blood. Zocor (Zocor) is also used to increase the level of HDL (good) cholesterol in your blood. These actions may reduce the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.
• Zocor may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Zocor?
• Do not take Zocor without first talking to your doctor if you have liver disease.
• Before taking Zocor, tell your doctor if you
· have kidney disease,
· drink alcoholic beverages,
· have a chronic muscular disease, or
· have a blood disorder.
• You may not be able to take Zocor, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Zocor is in the FDA pregnancy category X. This means that Zocor is known to cause birth defects if it is taken during pregnancy. Do not take Zocor if you are pregnant or could become pregnant during treatment.
• It is not known whether Zocor passes into breast milk. Do not take Zocor without first talking to your doctor if you are breast-feeding a baby.




How should I take Zocor?
• Take Zocor exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• For the greatest effect, Zocor is usually taken at bedtime or with an evening meal. Follow your doctor's instructions.
• Your doctor may want to monitor your liver function with blood tests before starting treatment with Zocor and every six months after both the start of your treatment and any increase in dose. Depending on the results of these tests, your doctor can determine how much monitoring you will require.
• Grapefruit and grapefruit juice may interact with Zocor. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
• Eat a low-fat, low-cholesterol diet. To realize beneficial effects from Zocor, avoid fatty, high-cholesterol foods.
• It is important to take Zocor regularly to get the most benefit.
• Do not stop taking Zocor without first talking to your doctor. Zocor may need to be taken on a long-term basis for the treatment of high cholesterol.
• Your doctor may want you to have blood tests or other medical evaluations during treatment with Zocor to monitor progress and side effects.
• Store Zocor at room temperature away from moisture and heat.




What happens if I miss a dose?
• Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.




What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected.
• Symptoms of a Zocor overdose include nausea, diarrhea, stomach distress, and indigestion.




What should I avoid while taking Zocor?
• Grapefruit and grapefruit juice may interact with Zocor. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
• Alcohol and Zocor can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined.




What are the possible side effects of Zocor?
• Rare cases of muscle problems and liver problems have been associated with the use of Zocor and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes, abdominal pain, unexplained fatigue, dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems.
• If you experience any of the following serious side effects, stop taking Zocor and seek emergency medical attention or contact your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
· decreased urine or rust-colored urine; or
· blurred vision.
• Other, less serious side effects may be more likely to occur. Continue to take Zocor and talk to your doctor if you experience
· gas, bloating, nausea, stomach upset, heartburn, abdominal pain, constipation, or diarrhea;
· cough;
· headache; or
· insomnia.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Zocor?
• Do not take Zocor without first talking to your doctor if you are taking any of the following medicines:
· cyclosporine (Sandimmune, Neoral);
· gemfibrozil (Lopid), clofibrate (Atromid-S), or fenofibrate (Tricor);
· niacin (Nicolar, Nicobid, Slo-Niacin, others);
· erythromycin (E-Mycin, E.E.S., Ery-Tab, others) or clarithromycin (Biaxin);
· cholestyramine (Questran) or colestipol (Colestid);
· an antifungal medication such as itraconazole (Sporanox), fluconazole (Diflucan), or ketoconazole (Nizoral);
· nefazodone (Serzone);
· digoxin (Lanoxin, Lanoxicaps);
· warfarin (Coumadin);
· a protease inhibitor such as amprenavir (Agenerase), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), lopinavir-ritonavir (Kaletra), or saquinavir (Invirase, Fortovase);
· amiodarone (Cordarone, Pacer one); or
· verapamil (Calan, Covera-HS, Isoptin, Verelan).
• You may not be able to take Zocor, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact with Zocor. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Zithromax

What is the most important information I should know about Zithromax?
• Do not use Zithromax if you have ever had an allergic reaction to this medicine or similar drugs such as erythromycin (E-Mycin, Ery-Tab, E.E.S.), clarithromycin (Biaxin), or other macrolide antibiotics.
• There are many other medicines that can interact with Zithromax. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
• Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Zithromax will not treat a viral infection such as the common cold or flu.
• Take Zithromax on an empty stomach 1 hour before or 2 hours after meals.
• Do not take Zithromax at the same time as taking an antacid that contains aluminum or magnesium. This includes Rolaids, Maalox, Mylanta, Milk of Magnesia, Pepcid Complete, and others. These antacids can make Zithromax less effective when taken at the same time.




What is Zithromax?
• Zithromax is in a group of drugs called macrolide antibiotics. Zithromax fights bacteria in the body.
• Zithromax is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases.
• Zithromax may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Zithromax?
• Do not use Zithromax if you have ever had an allergic reaction to this medicine or similar drugs such as erythromycin (E-Mycin, Ery-Tab, E.E.S.), clarithromycin (Biaxin), or other macrolide antibiotics.
• Before taking Zithromax, tell your doctor if you have:
· liver disease;
· kidney disease;
· a heart rhythm disorder; or
· a history of Long QT syndrome.
• If you have any of these conditions, you may not be able to use Zithromax, or you may need a dosage adjustment or special tests during treatment.
• FDA pregnancy category B. This medication is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
• It is not known whether Zithromax passes into breast milk or if it could harm a nursing baby. Do not take this medication without telling your doctor if you are breast-feeding a baby.




How should I take Zithromax?
• Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. The dose and length of treatment with Zithromax may not be the same for every type of infection.
• Take each tablet or capsule with a full glass (8 ounces) of water.
• To use the oral suspension single dose packet: Open the packet and pour the medicine into 2 ounces of water. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.
• Zithromax capsules must be taken on an empty stomach. Take the capsule at least 1 hour before or 2 hours after eating a meal
• Zithromax tablets or powder oral suspension may be taken with or without food. Take the tablet or oral suspension with food if the medicine upsets your stomach.
• Do not take Zithromax at the same time as taking an antacid that contains aluminum or magnesium. This includes Rolaids, Maalox, Mylanta, Milk of Magnesia, Pepcid Complete, and others. These antacids can make Zithromax less effective when taken at the same time.
• Shake the oral suspension (liquid) well just before you measure a dose. To be sure you get the correct dose, measure the liquid with a marked measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
• Take this medication for the entire length of time prescribed by your doctor. Your symptoms may get better before the infection is completely treated. Zithromax will not treat a viral infection such as the common cold or flu.
• It is important to take Zithromax regularly to get the most benefit.
• Store this medication at room temperature away from moisture and heat. Throw away any unused liquid medicine after 10 days.




What happens if I miss a dose?
• Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.




What happens if I overdose?
• Seek emergency medical attention if you think you have used too much of this medicine.
• Symptoms of an Zithromax overdose may include nausea, vomiting, diarrhea, and stomach discomfort.




What should I avoid while taking Zithromax?
• Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.
• Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Zithromax can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.




What are the possible side effects of Zithromax?
• Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
• Stop using Zithromax and call your doctor at once if you have any of these serious side effects:
· diarrhea that is watery or bloody;
· chest pain, uneven heartbeats; or
· nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
• Continue using Zithromax and talk with your doctor if you have any of these less serious side effects:
· mild nausea, vomiting, diarrhea, constipation, or stomach pain;
· dizziness, tired feeling, or headache;
· vaginal itching or discharge; or
· mild itching or skin rash.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Zithromax?
• Do not take antacids that contain aluminum or magnesium within 2 hours of taking Zithromax.
• Before taking Zithromax, tell your doctor if you are using any of the following drugs:
· nelfinavir (Viracept);
· digoxin (Lanoxin, Lanoxicaps);
· ergot medicine such as methysergide (Sansert), ergotamine (Ergostat, Medihaler, Cafergot, Ercaf, Wigraine), dihydroergotamine mesylate (D.H.E., Migranal Nasal Spray);
· triazolam (Halcion);
· carbamazepine (Carbatrol, Tegretol);
· cyclosporine (Neoral, Sandimmune);
· phenytoin (Dilantin);
· cholesterol-lowering medicines such as lovastatin (Mevacor), atorvastatin (Lipitor), or cerivastatin (Baycol);
· a calcium channel blocker such as diltiazem (Cartia XT, Diltiazem, Tiazac), felodipine (Plendil), nicardipine (Cardene), nifedipine (Procardia, Adalat), nimodipine (Nimotop), verapamil (Calan, Covera-HS);
· HIV medicines such as indinavir (Crixivan), ritonavir (Norvir), saquinavir (Invirase);
· alprazolam (Xanax), diazepam (Valium), midazolam (Versed), triazolam (Halcion);
· theophylline (Theo-Dur, Theolair, Theochron);
· warfarin (Coumadin);
· pimozide (Orap); or
· another antibiotic, especially clarithromycin (Biaxin) or erythromycin (E-Mycin, E.E.S, Ery-Tab).
• If you are using any of these drugs, you may not be able to use Zithromax, or you may need dosage adjustments or special tests during treatment.
• There are many other medicines that can interact with Zithromax. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Zetia

What is the most important information I should know about Zetia?
• Do not stop taking Zetia unless directed to do so by your doctor. It may be weeks or months before beneficial effects are seen from this medication.




What is Zetia?
• Zetia reduces the amount of cholesterol absorbed by the body.
• Zetia is used to reduce the amount of total cholesterol, LDL (bad) cholesterol, and apolipoprotein B (a protein needed to make cholesterol) in the blood. Zetia is used with a low cholesterol diet and, in some cases, other cholesterol lowering medications.
• Zetia may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Zetia?
• Before taking Zetia tell your doctor if you
· have liver disease;
· are taking another cholesterol-lowering medication; or
· have unexplained muscle pain, tenderness, or weakness.
• You may not be able to take Zetia, or you may require a dosage adjustment or special monitoring during treatment.
• Zetia is in the FDA pregnancy category C. This means that it is not known whether Zetia will be harmful to an unborn baby. Do not take Zetiawithout first talking to your doctor if you are pregnant or could become pregnant during treatment.
• It is not known whether Zetia passes into breast milk. Do not take Zetia without first talking to your doctor if you are breast-feeding a baby.




How should I take Zetia?
• Take Zetia exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Take Zetia once a day with or without food. It may be easier to remember to take the medication if you take it at the same time every day.
• Zetia should be taken 2 hours before or 4 hours after a bile acid sequestrant such as cholestyramine (Locholest, Prevalite, Questran), colestipol (Colestid), or colesevelam (Welchol).
• Eat a low-fat, low-cholesterol diet. To see beneficial effects from Zetia avoid fatty, high-cholesterol foods.
• Your doctor may want to monitor cholesterol levels, liver function, or other factors with blood tests before starting and during treatment with Zetia. Depending on the results of these tests, your doctor can determine how much monitoring you will require.
• Do not stop taking Zetia unless directed to do so by your doctor. It may be weeks or months before beneficial effects are seen from this medication.
• Store Zetia at room temperature away from moisture and heat.




What happens if I miss a dose of Zetia?
• Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of the medication.




What happens if I overdose with Zetia?
• Seek emergency medical attention.
• Symptoms of an Zetia overdose are not known.




What should I avoid while taking Zetia?
• Eat a low-fat, low-cholesterol diet. To see beneficial effects from Zetia avoid fatty, high-cholesterol foods.




What are the possible side effects of Zetia?
• If you experience an uncommon allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives), stop taking Zetia and seek emergency medical attention.
• Other, less serious side effects have also been reported, although uncommon. Continue to take Zetia and talk to your doctor if you experience
· abdominal pain;
· diarrhea; or
· tiredness.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Zetia?
• Before taking Zetia, tell your doctor if you are taking:
· another medicine to lower cholesterol such as gemfibrozil (Lopid), fenofibrate (Tricor), clofibrate (Atromid-S), atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Altocor, Mevacor), pravastatin (Pravachol), or simvastatin (Zocor).
· cyclosporine (Sandimmune, Neoral, Gengraf).
• You may not be able to take Zetia, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medications listed above.
• Zetia should be taken 2 hours before or 4 hours after a bile acid sequestrant such as cholestyramine (Locholest, Prevalite, Questran), colestipol (Colestid), or colesevelam (Welchol).
• Drugs other than those listed here may also interact with cholestyramine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Yasmin

What is the most important information I should know about Yasmin?
• This medication can cause birth defects in an unborn baby. Do not use if you are pregnant. Use an effective form of birth control, and tell your doctor if you become pregnant during treatment.
• Yasmin will not protect you from sexually transmitted diseases--including HIV or AIDS.
• Avoid smoking cigarettes while taking Yasmin. Smoking greatly increases the risk of heart attack, stroke, and blood clot.
• Drospirenone may raise potassium levels in your blood. Other medical conditions can also affect potassium levels. Before using Yasmin, tell your doctor about all of your current and past medical conditions, and about all the medicines you use.
• Many other drugs can interact with Yasmin and make this medication less effective, increasing your risk of unintended pregnancy. Tell your doctor about all the prescription and over-the-counter medications you use, including vitamins, minerals, herbal products, and drugs prescribed by other doctors.
• Stop using this medication and call your doctor at once if you feel short of breath, have sudden numbness or weakness on one side of the body, sudden headache, confusion, or problems with vision, speech, or balance.
• Call your doctor right away if you have a breast lump, unusual vaginal bleeding, or jaundice (yellowing of the skin or eyes).




What is Yasmin?
• Drospirenone and ethinyl estradiol are female hormones involved in conception.
• Yasmin is used to prevent pregnancy. This medication works by preventing ovulation (the release of an egg from an ovary).
• Yasmin may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Yasmin
• Drospirenone may raise potassium levels in your blood. Other medical conditions can also affect potassium levels. Before using Yasmin, tell your doctor if you have any of the following:
· a history of liver disease;
· a history of jaundice (yellowing of the skin or eyes) during a pregnancy or while using birth control pills;
· kidney disease;
· adrenal insufficiency;
· hemophilia or other bleeding disorder;
· unusual vaginal bleeding; or
· any type of breast, uterine, or hormone-dependent cancer.
• Certain medicines can also affect potassium levels. Tell your doctor if you use any of the following drugs:
· heparin;
· aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as celecoxib (Celebrex), diclofenac (Voltaren), ibuprofen (Motrin, Advil), indomethacin, naproxen (Aleve, Naprosyn), piroxicam (Feldene);
· a diuretic ("water pill") such as spironolactone (Aldactone), triamterene (Dyrenium, Dyazide, Maxzide), amiloride (Midamor), or eplerenone (Inspra);
· a potassium supplement such as Klor-Con, K-Dur, K-Tab;
· an ACE inhibitor such as benazepril (Lotensin), lisinopril (Prinivil, Zestril), enalapril (Vasotec); or
· blood pressure medicine such as candesartan (Atacand), losartan (Cozaar), telmisartan (Micardis).
• If you have any of the following conditions, you may not be able to use Yasmin, or you may need a dosage adjustment or special tests during treatment:
· high blood pressure, angina, heart disease, high cholesterol or triglycerides;
· a history of stroke or blood clot;
· liver or kidney disease;
· asthma;
· epilepsy;
· migraines, depression;
· diabetes;
· gallbladder disease;
· uterine fibroids; or
· you have had a hysterectomy (uterus removed).
• FDA pregnancy category X. This medication can cause birth defects. Do not use this medication if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
• Yasmin may affect breast milk. Do not take Yasmin without telling your doctor if you are breast-feeding a baby.




How should I take Yasmin?
• Take this medication exactly as it was prescribed for you. Do not take the medication in larger or smaller amounts, or take it for longer than recommended by your doctor.
• Take the first pill in a package on the first day of your period or on the first Sunday after your period begins as directed by your doctor.
• Take one pill every day, no more than 24 hours apart. Try to take the pills at the same time each day to help you remember.
• Taking the pill at night may reduce noticeable side effects such as headache or nausea.
• If you are on a 28-day cycle, take one pill every day. When the pack runs out, throw it away. Begin a new pack the following day. The 28-day cycle contains seven pills that are placebos (with no active ingredients). These are "reminder" pills to keep you on a regular cycle. You will take them while you are on your period.
• You may need to use a backup method of birth control when you first start taking drosperinone and ethinyl estradiol or if you miss a pill. You may also need another form of birth control whenever you use certain other medicines. Some drugs can make birth control pills less effective and you could become pregnant. Follow your doctor's instructions for using a second form of birth control if you have any of these situations.
• See your doctor yearly for physical exams. Check your breasts for lumps monthly while you are taking Yasmin. Your doctor may also want to test the potassium levels in your blood. It is important that you not miss any scheduled appointments with your doctor.
• Yasmin will not protect you from sexually transmitted diseases--including HIV or AIDS.
• Store Yasmin at room temperature away from moisture and heat.




What happens if I miss a dose?
• Missing a pill increases your risk of becoming pregnant. Follow the directions on the patient information sheet provided with your medicine. If you do not have an information sheet, call your doctor for instructions if you miss a dose.
• If you miss one yellow "active" pill, take the dose as soon as you remember or take two pills at the time of your next regularly scheduled dose. You do not need to use backup birth control.
• If you miss two yellow "active" tablets in a row in week one or two, take two tablets each for the next two regularly scheduled doses (one missed tablet plus one regularly scheduled tablet for 2 days in a row). Use another form of birth control for at least 7 days following the missed tablets.
• If you miss two yellow "active" tablets in a row in week three, or if you miss three tablets in a row during any of the first 3 weeks, throw out the rest of the pack and start a new package on the same day if you are a Day 1 starter. If you are a Sunday starter, keep taking a pill every day until Sunday. On Sunday, throw out the rest of the pack and start a new pack of pills that same day. You may not have a period that month, but this is expected. However, if you miss your period 2 months in a row, call your doctor because you might be pregnant.
• If you miss one of the reminder pills in week four, skip that dose and take the next one as directed.
• If you miss a pill, you may become pregnant if you have sex in the 7 days after your missed pill. You MUST use another birth control method (such as condoms or spermicides) as a back-up for those 7 days.




What happens if I overdose?
• Seek emergency medical attention if you think you have used too much of this medicine.
• An overdose of Yasmin is not expected to produce life-threatening symptoms.




What should I avoid while taking Yasmin
• Avoid smoking cigarettes while taking Yasmin. Smoking greatly increases the risk of heart attack, stroke, and blood clot.




What are the possible side effects of Yasmin?
• Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
• Stop using this medication and call your doctor at once if you have any of these serious side effects:
· chest pain;
· shortness of breath;
· sudden numbness or weakness, especially on one side of the body;
· sudden headache, confusion, problems with vision, speech, or balance;
· unusual vaginal bleeding;
· stomach pain, swelling, or tenderness;
· jaundice (yellowing of the skin or eyes); or
· breast lump.
• Continue using Yasmin and talk with your doctor if you have any of these less serious side effects:
· nausea and vomiting;
· breast tenderness or enlargement;
· swelling of your hands or feet;
· darkened skin, especially on your face;
· changes in your menstrual periods;
· headache, migraine, dizziness, or fainting;
· problems with contact lenses;
· depression;
· vaginal yeast infections; or
· enlargement of uterine fibroids.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Yasmin?
• Before taking this medication, tell your doctor if you are using any of the following drugs:
· rifampin (Rifadin, Rimactane, Rifater);
· seizure medicine such as phenytoin (Dilantin), phenobarbital (Luminal), carbamazepine (Tegretol);
· an antibiotic such as ampicillin (Omnipen, Totacillin), tetracycline (Brodspec, Sumycin, Panmycin) or griseofulvin (Fulvicin);
· a potassium supplement such as Klor-Con, K-Dur, K-Tab;
· atorvastatin (Lipitor); or
· St. John's wort.
• If you are using any of these drugs, you may not be able to use dropirenone and estradiol.
• Many other drugs can interact with Yasmin and make this medication less effective, increasing your risk of unintended pregnancy. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Xenical

What is the most important information I should know about Xenical?
• Xenical may decrease your body's absorption of some fat-soluble vitamins. To ensure adequate nutrition, your doctor may recommend taking a multivitamin that contains vitamins D, E, K, and beta-carotene. Take your vitamin supplement once a day, at least 2 hours before or after a dose of Xenical.
• Do not take more of this medication than has been prescribed for you. Doses greater than 120 mg three times a day have not been shown to provide any additional weight-loss benefit.




What is Xenical?
• Xenical blocks some of the fat that you eat from being absorbed by your body.
• Xenical is used in the management of obesity including weight loss and weight maintenance when used with a reduced-calorie diet.
• Xenical may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Xenical?
• Do not take Xenical without first talking to your doctor if you have
· a chronic malabsorption syndrome, or
· gallbladder problems.
• You may not be able to take Xenical if you have any of the conditions listed above.
• Before taking Xenical, talk to your doctor if you
· have a history of kidney stones,
· have diabetes,
· have anorexia or bulimia,
· take any other weight-loss medicine, or
· take cyclosporine (Sandimmune, Neoral).
• You may not be able to take Xenical, or you may require a dosage adjustment or special monitoring during your treatment if you have any of the conditions listed above.
• Xenical is in the FDA pregnancy category B. This means that it is not expected to harm an unborn baby. Do not take Xenical without first talking to your doctor if you are pregnant.
• It is not known whether Xenical passes into breast milk. Do not take Xenical without first talking to your doctor if you are breast-feeding a baby.




How should I take Xenical?
• Take Xenical exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Xenical is usually taken with each main meal that contains fat. Xenical can be taken during meals or up to one hour after a meal.
• Each time you take Xenical, your meal should contain no more than about 30% of calories from fat. Evenly divide your daily intake of fat, carbohydrates, and protein over three main meals a day. Talk to your doctor about following a healthy eating plan.
• If you miss a meal, or if you have a meal without fat, you can skip your dose of Xenical for that meal also.
• If Xenical is taken with any one meal that is very high in fat, there is an increased chance of digestive side effects.
• Do not take more of this medication than has been prescribed for you. Doses greater than 120 mg three times a day have not been shown to provide an additional weight-loss benefit.
• Xenical may decrease your body's absorption of some fat-soluble vitamins. To ensure adequate nutrition, your doctor may recommend taking a multivitamin that contains vitamins D, E, K, and beta-carotene. Take your vitamin supplement once a day, at least 2 hours before or after a dose of Xenical.
• Store Xenical at room temperature away from moisture and heat.




What happens if I miss a dose?
• Take the missed dose up to one hour after a meal. If more than one hour has passed since your last meal, skip the dose you missed and take only your next regularly scheduled dose as directed. Do not take a double dose of this medication.
• If you miss a meal, or if you have a meal without fat, you can skip your dose of Xenical for that meal also.




What happens if I overdose?
• Seek emergency medical attention.
• Symptoms of an Xenical overdose are not known.




What should I avoid while taking Xenical?
• Xenical may decrease your body's absorption of some fat-soluble vitamins. To ensure adequate nutrition, your doctor may recommend taking a multivitamin that contains vitamins D, E, K, and beta-carotene. Take your vitamin supplement once a day, at least 2 hours before or after a dose of Xenical.
• Each time you take Xenical, your meal should contain no more than about 30% of calories from fat. Evenly divide your daily intake of fat, carbohydrates, and protein over three main meals a day. Talk to your doctor about following a healthy eating plan.




What are the possible side effects of Xenical?
• Stop taking Xenical and seek emergency medical attention if you experience a rare allergic reaction including shortness of breath; closing of your throat; swelling of your lips, tongue, or face; or hives.
• Other, less serious side effects are more likely to occur. Continue to take Xenical and talk to your doctor if you experience
· oily spotting,
· gas with discharge,
· an urgent need to go to the bathroom,
· oily or fatty stools,
· an oily discharge,
· an increased number of bowel movements,
· an inability to control bowel movements, or
· orange or brown colored oil in your stool.
• The bowel changes listed above are a natural effect of blocking fat and indicate that Xenical is working. They generally occur early in treatment, particularly after meals containing higher amounts of fat than are recommended. These symptoms are usually temporary and lessen or disappear as you continue treatment and keep to your recommended diet of meals containing 30% fat.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Xenical?
• Do not take Xenical without first talking to your doctor if you are taking any of the following medicines:
· cyclosporine (Neoral, Sandimmune), or
· warfarin (Coumadin).
• You may not be able to take Xenical, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.
• Before taking Xenical, tell your doctor if you are taking any of the following medicines to lower cholesterol:
· atorvastatin (Lipitor),
· cerivastatin (Baycol),
· fluvastatin (Lescol),
· lovastatin (Mevacor),
· pravastatin (Pravachol), or
· simvastatin (Zocor).
• You may require a dosage adjustment or special monitoring during treatment if you are taking any of the cholesterol-lowering medicines listed above.
• Xenical may decrease your body's absorption of some fat-soluble vitamins. To ensure adequate nutrition, your doctor may recommend taking a multivitamin that contains vitamins D, E, K, and beta-carotene. Take your vitamin supplement once a day, at least 2 hours before or after a dose of Xenical.
• Drugs other than those listed here may also interact with Xenical. Talk to your doctor and pharmacist before taking or using any other prescription or over-the-counter medicines.

Xanax

What is the most important information I should know about Xanax?
• Use caution when driving, operating machinery, or performing other hazardous activities. Xanax will cause drowsiness and may cause dizziness. If you experience drowsiness or dizziness, avoid these activities.
• Avoid alcohol while taking Xanax. Alcohol may increase drowsiness and dizziness caused by Xanax.
• Do not crush, chew, or break the extended-release form Xanax XR. Swallow them whole. These tablets are specially formulated to release the medication slowly in the body.
• Xanax is habit forming. You can become physically and psychologically dependent on the medication. Do not take more than the prescribed amount of medication or take it for longer than is directed by your doctor. Withdrawal effects may occur if Xanax is stopped suddenly after several weeks of continuous use. Seizures may be a side effect of sudden discontinuation of the medication. Your doctor may recommend a gradual reduction in dose.




What is Xanax?
• Xanax is in a class of drugs called benzodiazepines. Xanax affects chemicals in the brain that may become unbalanced and cause anxiety.
• Xanax is used to relieve anxiety, nervousness, and tension associated with anxiety disorders. Xanax is also used to treat panic disorders.
• Xanax may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Xanax?
• Do not take Xanax if you have narrow-angle glaucoma. Xanax may worsen this condition.
• Before taking this medication, tell your doctor if you
· have kidney disease;
· have liver disease;
· have a history of alcohol or drug abuse;
· have asthma, bronchitis, emphysema, or another respiratory disease;
· are depressed or have suicidal thoughts; or
· have mania, bipolar disorder, or another psychiatric condition (other than anxiety or panic disorder).
• You may not be able to take Xanax, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Xanax is in the FDA pregnancy category D. This means that Xanax is known to be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment.
• It is not known whether Xanax passes into breast milk. Do not take Xanax without first talking to your doctor if you are breast-feeding a baby.
• If you are over 65 years of age, you may be more likely to experience side effects from Xanax. Your doctor may prescribe a lower dose of the medication.




How should I take Xanax?
• Take Xanax exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Do not crush, chew, or break the extended-release form Xanax XR. Swallow them whole. These tablets are specially formulated to release the medication slowly in the body.
• Do not take more of the medication than is prescribed for you.
• Xanax is habit forming. You can become physically and psychologically dependent on the medication. Do not take more than the prescribed amount of medication or take it for longer than is directed by your doctor. Withdrawal effects may occur if Xanax is stopped suddenly after several weeks of continuous use. Seizures may be a side effect of sudden discontinuation of the medication. Your doctor may recommend a gradual reduction in dose.
• Store Xanax at room temperature away from moisture and heat.




What happens if I miss a dose?
• Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication. A double dose could be dangerous.




What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected.
• Symptoms of an Xanax overdose include sleepiness, dizziness, confusion, a slow heart beat, difficulty breathing, difficulty walking and talking, an appearance of being drunk, and unconsciousness.




What should I avoid while taking Xanax?
• Use caution when driving, operating machinery, or performing other hazardous activities. Xanax will cause drowsiness and may cause dizziness. If you experience drowsiness or dizziness, avoid these activities.
• Avoid alcohol while taking Xanax. Alcohol may increase drowsiness and dizziness caused by Xanax.
• Xanax may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any other medicine without first talking to your doctor.




What are the possible side effects of Xanax?
• If you experience any of the following serious side effects, stop taking Xanax and seek emergency medical attention or contact your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, face, or tongue; or hives);
· sores in the mouth or throat;
· yellowing of the skin or eyes;
· a rash;
· hallucinations or severe confusion; or
· changes in vision.
• Other, less serious side effects may be more likely to occur. Continue to take Xanax and talk to your doctor if you experience
· drowsiness, dizziness, or clumsiness;
· depression;
· nausea, vomiting, diarrhea, or constipation;
· difficulty urinating;
· vivid dreams;
· headache;
· dry mouth;
· decreased sex drive; or
· changes in behavior.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Xanax?
• Do not take ketoconazole (Nizoral) or itraconazole (Sporanox) during treatment with Xanax without first talking to your doctor.
• Xanax may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor.
• Antacids may decrease the effects of Xanax. Separate doses of an antacid and Xanax by several hours whenever possible.
• Drugs other than those listed here may also interact with Xanax. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

Wellbutrin

What is the most important information I should know about Wellbutrin?
You should not take Wellbutrin if you have epilepsy or a seizure disorder, an eating disorder such as anorexia or bulimia, if you are using a second form of bupropion, or if you have suddenly stopped using alcohol or sedatives. Do not take Wellbutrin if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl), or tranylcypromine (Parnate) in the last 14 days.
You may have an increased risk of suicidal thoughts or behavior at the start of treatment with an antidepressant medication, especially if you are 18 years of age or younger. Talk with your doctor about this risk. While you are taking this medication you will need to be monitored for worsening symptoms of depression and/or suicidal thoughts during the first weeks of treatment, or whenever your dose is changed. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Contact your doctor if you have any of the following side effects, especially if they are new symptoms or if they get worse: mood changes, anxiety, panic attacks, trouble sleeping, irritability, agitation, aggressiveness, severe restlessness, mania (mental and/or physical hyperactivity), or thoughts of suicide or hurting yourself.

Do not stop taking Wellbutrin without first talking to your doctor. You may have unpleasant side effects if you stop taking this medication suddenly.
Avoid using bupropion to treat more than one condition at a time. If you take Wellbutrin for depression, do not also take Zyban to quit smoking. Too much of this medicine can increase your risk of a seizure.

Do not smoke at any time if you are using a nicotine product along with Zyban. Too much nicotine can cause serious side effects. Avoid drinking alcohol while taking Wellbutrin. Alcohol may increase your risk of a seizure while you are taking Wellbutrin. If you drink alcohol regularly, talk with your doctor before changing the amount you drink. Wellbutrin can cause seizures in people who drink a lot of alcohol and then suddenly quit drinking when they start using the medication.
There are many other drugs that can affect Wellbutrin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


What is Wellbutrin?
Wellbutrin is an antidepressant medication.

Wellbutrin is used to treat major depressive disorder and seasonal affective disorder.

At least one brand of bupropion (Zyban) is used to help people stop smoking by reducing cravings and other withdrawal effects.

Wellbutrin may also be used for purposes other than those listed in this medication guide.


What should I discuss with my healthcare provider before taking Wellbutrin?
Do not take Wellbutrin if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl), or tranylcypromine (Parnate) in the last 14 days. You should not take Wellbutrin if you have:
epilepsy or a seizure disorder;

an eating disorder such as anorexia or bulimia;

if you are using a second form of bupropion; or

if you have suddenly stopped using alcohol or sedatives (such as Valium).

Before taking Wellbutrin, tell your doctor if you have:

heart disease or high blood pressure;

head injury, brain or spinal cord tumor;

kidney disease;

liver disease (especially cirrhosis);

bipolar disorder (manic depression);

diabetes for which you use insulin or take oral medication;

current use of steroids, theophylline (Theo-Dur, Slo-Bid, Bronkodyl Theolair, Respbid), or medicine to treat depression or mental illness; or

recent use of alcohol, sedatives (such as Valium), narcotic pain medicines, diet pills, or street drugs such as "speed" or cocaine.

If you have any of these conditions, you may not be able to use Wellbutrin, or you may need a dosage adjustment or special tests during treatment.

Wellbutrin may cause seizures, especially in people with certain medical conditions or when using certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

You may have an increased risk of suicidal thoughts or behavior at the start of treatment with an antidepressant medication, especially if you are under 18 years old. While you are taking Wellbutrin, you will need to be monitored for worsening symptoms of depression and/or suicidal thoughts during the first weeks of treatment, or whenever your dose is changed. In addition to you watching for changes in your own symptoms, your family or other caregivers should be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Contact your doctor if you have any of the following side effects, especially if they are new symptoms or if they get worse: mood changes, anxiety, panic attacks, trouble sleeping, irritability, agitation, aggressiveness, severe restlessness, mania (mental and/or physical hyperactivity), or thoughts of suicide or hurting yourself.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Wellbutrin passes into breast milk and could be harmful to a nursing baby. Do not take Wellbutrin without telling your doctor if you are breast-feeding a baby.

How should I take Wellbutrin?
Take Wellbutrin exactly as it was prescribed for you. Do not take it in larger doses or for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from the medication.

Wellbutrin can be taken with or without food.

Take each dose with a full glass of water. Do not crush, chew, or break the extended-release tablet (Wellbutrin SR, Wellbutrin XL, Zyban SR). Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.
If you take Zyban to help you stop smoking, you may continue to smoke for about 1 week after you start the medicine. Set a date to quit smoking during the second week of Zyban treatment. By that time you will have enough of the medicine in your blood stream to help you quit smoking. Talk to your doctor if you are having trouble quitting after you have used Zyban for at least 7 weeks.

Your doctor may prescribe nicotine patches or gum to help support your smoking cessation treatment. Be sure you read all directions and safety information for the nicotine product. Using nicotine with Zyban may raise your blood pressure and your doctor may want to check your blood pressure regularly. Do not smoke at any time if you are using a nicotine product along with Zyban. Too much nicotine can cause serious side effects.

Do not stop taking Wellbutrin without first talking to your doctor. You may have unpleasant side effects if you stop taking this medication suddenly.
If you use the Wellbutrin extended-release tablet, the tablet shell may pass into your stools (bowel movements). This is normal and does not mean that you are not receiving enough of the medicine.

Store Wellbutrin at room temperature away from moisture and heat.

What happens if I miss a dose of Wellbutrin?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose with Wellbutrin?
Seek emergency medical attention if you think you have used too much of this medicine. Symptoms of a Wellbutrin overdose may include seizures, muscle stiffness, hallucinations, fainting, fast or uneven heartbeat, shallow breathing, heart failure, or coma.

What should I avoid while taking Wellbutrin?
Avoid drinking alcohol while taking Wellbutrin. Alcohol may increase your risk of a seizure while you are taking Wellbutrin. If you drink alcohol regularly, talk with your doctor before changing the amount you drink. Wellbutrin can cause seizures in people who drink a lot of alcohol and then suddenly quit drinking when they start using the medication.
Avoid using bupropion to treat more than one condition at a time. If you take Wellbutrin for depression, do not also take Zyban to quit smoking. Too much of this medicine can increase your risk of a seizure.

Wellbutrin can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

What are the possible side effects of Wellbutrin?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Wellbutrin and call your doctor at once if you have a seizure (convulsions) or fast, uneven heartbeats.
Continue taking Wellbutrin and talk to your doctor if you have any of these less serious side effects:

headache or migraine;

sleep problems (insomnia);

nausea, vomiting, constipation, dry mouth;

confusion, dizziness, agitation, tremors (shaking);

appetite changes, weight loss or gain;

mild itching or skin rash, increased sweating; or

loss of interest in sex.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.


What other drugs will affect Wellbutrin?
Do not take Wellbutrin if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl), or tranylcypromine (Parnate) in the last 14 days.

There are many other drugs that can affect Wellbutrin. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.


Where can I get more information on Wellbutrin?
Your pharmacist has more information about Wellbutrin written for health professionals that you may read.

Vytorin

What is the most important information I should know about Vytorin?
• Do not stop taking Vytorin unless directed to do so by your doctor. It may be weeks or months before beneficial effects are seen from this medication.
• Rare cases of muscle problems and liver problems have been associated with the use of Vytorin and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes, abdominal pain, unexplained fatigue, dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems.
• Do not take Vytorin without first talking to your doctor if you have liver disease.
• Alcohol and Vytorin can both be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined.
• Do not take Vytorin if you are pregnant, could become pregnant during treatment, or if you are breast-feeding a baby.




What is Vytorin?
• Vytorin reduces the amount of cholesterol (a type of fat) absorbed by the body and blocks the production of cholesterol in the body.
• Vytorin is used to reduce the total amounts of cholesterol, LDL (bad) cholesterol, triglycerides (another type of fat), and apolipoprotein B (a protein needed to make cholesterol) in your blood. Vytorin is also used to increase the level of HDL (good) cholesterol in your blood. These actions may reduce the risk of hardening of the arteries, which can lead to heart attacks, stroke, and peripheral vascular disease.
• Vytorin may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Vytorin?
• Before taking Vytorin, tell your doctor if you
· have liver or kidney disease;
· drink alcoholic beverages;
· have hypothyroidism (low thyroid function);
· have a chronic muscular disease or have unexplained muscle pain, tenderness, or weakness;
· are taking another cholesterol-lowering medication; or
· have a blood disorder.
• You may not be able to take Vytorin, or you may require a dosage adjustment or special monitoring during treatment.
• Vytorin is in the FDA pregnancy category X. This means that Vytorin is known to cause birth defects if it is taken during pregnancy. Do not take Vytorin if you are pregnant or could become pregnant during treatment.
• It is not known whether Vytorin passes into breast milk. Do not take simvastatin without first talking to your doctor if you are breast-feeding a baby.




How should I take Vytorin?
• Take Vytorin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take Vytorin once a day with or without food. It may be easier to remember to take the medication if you take it at the same time every day.
• Vytorin should be taken 2 hours before or 4 hours after a bile acid sequestrant such as cholestyramine (Locholest, Prevalite, Questran), colestipol (Colestid), or colesevelam (Welchol).
• Your doctor may want to monitor cholesterol levels, liver function, or other factors with blood tests before starting and during treatment with Vytorin. Depending on the results of these tests, your doctor can determine how much monitoring you will require.
• Do not stop taking Vytorin unless directed to do so by your doctor. It may be weeks or months before beneficial effects are seen from this medication.
• Store Vytorin at room temperature away from moisture and heat.




What happens if I miss a dose?
• Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of the medication.




What happens if I overdose?
• Seek emergency medical attention if an overdose is suspected.
• Symptoms of an Vytorin overdose may include nausea, diarrhea, stomach distress, and indigestion..




What should I avoid while taking Vytorin?
• Eat a low-fat, low-cholesterol diet. To see beneficial effects from Vytorin avoid fatty, high-cholesterol foods.
• Grapefruit and grapefruit juice may interact with Vytorin. The interaction could lead to potentially dangerous effects. Discuss the use of grapefruit and grapefruit juice with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
• Both alcohol and ezetimibe/simvastatin can be damaging to the liver. Alcohol should be used only in moderation. Discuss the use of alcohol with your doctor so that the potential for liver problems can be determined.
• Avoid prolonged exposure to sunlight or artificial UV light (e.g., tanning beds). Vytorin may increase the sensitivity of the skin to sunlight, and burning may result. Wear protective clothing and sunscreen if exposure to the sun is unavoidable.




What are the possible side effects of Vytorin?
• Rare cases of muscle problems and liver problems have been associated with the use of Vytorin and other similar medicines. Contact your doctor immediately if you experience unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or flulike symptoms or yellowing of the skin or eyes, abdominal pain, unexplained fatigue, dark colored urine or pale colored stools. These may be early symptoms of muscle or liver problems.
• If you experience any of the following serious side effects, stop taking Vytorin and seek emergency medical attention or contact your doctor immediately:
· an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
· decreased urine or rust-colored urine; or
· blurred vision.
• Other, less serious side effects may be more likely to occur. Continue to take Vytorin and talk to your doctor if you experience
· gas, bloating, nausea, stomach upset, heartburn, abdominal pain, constipation, or diarrhea;
· cough;
· tiredness;
· headache; or
· insomnia.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Vytorin?
• Do not take Vytorin without first talking to your doctor if you are taking any of the following medicines:
· cyclosporine (Sandimmune, Neoral);
· atorvastatin (Lipitor), fluvastatin (Lescol), lovastatin (Altocor, Mevacor), pravastatin (Pravachol), rosuvastatin (Crestor) or simvastatin (Zocor);
· gemfibrozil (Lopid), fenofibrate (Tricor) or clofibrate (Atromid-S);
· niacin (Nicolar, Nicobid, Slo-Niacin, others);
· erythromycin (E-Mycin, E.E.S., Ery-Tab, others), telithromycin (Ketek) or clarithromycin (Biaxin);
· cholestyramine (Questran) or colestipol (Colestid);
· an antifungal medication such as itraconazole (Sporanox), fluconazole (Diflucan), or ketoconazole (Nizoral);
· nefazodone (Serzone);
· digoxin (Lanoxin, Lanoxicaps);
· warfarin (Coumadin);
· a protease inhibitor such as amprenavir (Agenerase), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), lopinavir-ritonavir (Kaletra), or saquinavir (Invirase, Fortovase);
· amiodarone (Cordarone, Pacer one); or
· verapamil (Calan, Covera-HS, Isoptin, Verelan).
• You may not be able to take Vytorin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact with Vytorin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.