Biaxin

What is the most important information I should know about Biaxin?
• Take all of the Biaxin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.
• Do not take Biaxin if you are taking cisapride (Propulsid), pimozide (Orap), or terfenadine (Seldane). These medicines can interact, possibly leading to a dangerous irregular heartbeat pattern.




What is Biaxin?
• Biaxin is in a class of drugs called macrolide antibiotics. Biaxin fights bacteria in your body.
• Biaxin is used to treat many different types of bacterial infections, such as bronchitis, pneumonia, sinusitis, tonsillitis, skin infections, and stomach ulcers caused by bacteria.
• Biaxin may also be used for purposes other than those listed in this medication guide.




What should I discuss with my healthcare provider before taking Biaxin?
• Do not take Biaxin if you are taking cisapride (Propulsid), pimozide (Orap), or terfenadine (Seldane). These medicines can interact, possibly leading to a dangerous irregular heartbeat pattern.
• Before taking Biaxin, tell your doctor if you have liver or kidney disease. You may not be able to take Biaxin, or you may require a lower dose and special monitoring during therapy.
• Biaxin is in the FDA pregnancy category C. This means that it is not known whether Biaxin will harm an unborn baby. Do not take Biaxin without first talking to your doctor if you are pregnant.
• It is not known whether Biaxin passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.




How should I take Biaxin?
• Take Biaxin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass (8 ounces) of water.
• Biaxin can be taken with food or milk or on an empty stomach.
• Take extended release clarithromycin (Biaxin XL) with food.
• Biaxin is usually taken two times a day with the doses about 12 hours apart. Follow your doctor's instructions.
• Shake the suspension well before measuring each dose. To ensure that you get a correct dose, measure the suspension with a dose-measuring dropper, cup, or spoon, not a regular tablespoon. Ask your pharmacist for a dose-measuring device if you do not have one.
• Take all of the Biaxin that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infection is completely treated.
• Store this medication at room temperature away from moisture and heat. Do not refrigerate the suspension.




What happens if I miss a dose?
• Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication unless otherwise directed by your doctor.




What happens if I overdose?
• Seek emergency medical attention.
• Symptoms of an Biaxin overdose include nausea, vomiting, diarrhea, and abdominal discomfort.




What should I avoid while taking Biaxin?
• Do not take Biaxin if you are taking cisapride (Propulsid), pimozide (Orap), or terfenadine (Seldane). These medicines can interact, possibly leading to a dangerous irregular heartbeat pattern.




What are the possible side effects of Biaxin?
• If you experience any of the following serious side effects, stop taking Biaxin and seek emergency medical attention:
· an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives), or
· liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).
• Other, less serious side effects may be more likely to occur. Continue to take Biaxin and talk to your doctor if you experience
· nausea, vomiting, diarrhea, or abdominal pain;
· dizziness, fatigue, or headache;
· a rash; or
· vaginal yeast infection.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.




What other drugs will affect Biaxin?
• Biaxin may cause dangerous side effects when taken with the following drugs:
· antihistamines such as terfenadine (Seldane) and astemizole (Hismanal);
· seizure medications such as carbamazepine (Tegretol), phenytoin (Dilantin), and valproic acid (Depakote, Depakene);
· asthma medications such as theophylline (Theo-Dur, Theolair, Theochron, others);
· anticoagulants (blood thinners) such as warfarin (Coumadin);
· heart medications for irregular heartbeats, such as digoxin (Lanoxin) and disopyramide (Norpace);
· Ergotamine (ergostat) or dihydroergotamine (D.H.E.);
· HMG-COA Reductase Inhibitors such as atorvastin (Lipitor), simvastatin (Zocor), lovastatin (Mevacor) and others;
· Benzodiazepines such as diazepam (Valium), triazolam (Halcion), alprazolam (Xanax) and others;
· sildenafil (Viagra) or vardenafil (Levitra); or
· other antibiotics. Do not use other antibiotics unless they are prescribed by your doctor.
• Do not take Biaxin without first talking to your doctor if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact with Biaxin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.




Where can I get more information?
• Your pharmacist has additional information about Biaxin written for health professionals that you may read.



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• Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
• Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.